Episodes

3 days ago
3 days ago
The Chromogen Siblings return to talk about small cell lung carcinomas. Drs. Mike Arnold (@MArnold_PedPath), Andrew Bellizzi (@IHC_guy), and Sanam Loghavi (@sanamloghavi) speak with Dr. Natasha Rekhtman (@natasharekhtman) of Memorial Sloan Kettering Cancer Center. Hear about how Pathologists use IHC to identify subsets of small cell lung carcinomas, and the cycle of how molecular data informs IHC approaches and histologic classifications in Pathology.
Featured articles:
SCLC Subtypes Defined by ASCL1, NEUROD1, POU2F3, and YAP1: A Comprehensive Immunohistochemical and Histopathologic Characterization
https://www.jto.org/article/S1556-0864(20)30755-3/fulltext
POU2F3 in SCLC: Clinicopathologic and Genomic Analysis With a Focus on Its Diagnostic Utility in Neuroendocrine-Low SCLC
https://linkinghub.elsevier.com/retrieve/pii/S1556-0864(22)00299-4
Featured public domain music: Alpha Hydrae, Won't see it comin'

Friday Jun 20, 2025
Beyond the Scope: Genitourinary Pathology with Dr. Sean Williamson
Friday Jun 20, 2025
Friday Jun 20, 2025
In this segment, Beyond the Scope, we speak to pathologists about their pursuits and interests in and outside of pathology.
Links to papers referenced in the episode:
SDH-deficient RCC: https://pubmed.ncbi.nlm.nih.gov/25034258/
RCC staging survey: https://pubmed.ncbi.nlm.nih.gov/29878933/
IJSP website: https://journals.sagepub.com/home/IJS

Friday May 23, 2025
PathPod's 5th Birthday
Friday May 23, 2025
Friday May 23, 2025
In this episode, we celebrate PathPod's 5th Birthday by listening back to the first ever PathPod Quiz Show from April 30, 2020.
Happy Birthday PathPod!

Friday Apr 18, 2025
IHC Talk: AI in Pathology and IHC with Dr. Matt Cecchini
Friday Apr 18, 2025
Friday Apr 18, 2025
In this edition of IHC Talk, Dr. Mike Arnold (@MArnold_PedPath), Dr. Andrew Bellizzi (@IHC_guy), and Dr. Sanam Loghavi (@sanamloghavi) delve into the exciting (and sometimes intimidating!) world of Artificial Intelligence and its potential to revolutionize pathology. They're joined by special guest Dr. Matt Cecchini (@Path_Matt), a pathologist with a keen interest in AI.
What you'll discover:
- Matt's unorthodox path to Pathology
- The role of IHC in conjunction with AI.
- The need for rigor and consistency in data
- How can the practicing pathologist work with AI to improve?
Get ready for a lively discussion that covers everything from image analysis and mitigating bias to AI agents. The crew dives deep into real-world examples, current tools like ChatGPT, and even the ethical considerations as AI takes on more responsibilities in diagnostic settings. Is AI about to replace pathologists, or can it augment our abilities to deliver better patient care? Listen in and explore the possibilities with this engaging episode!
Thanks to Dr. Cecchini for using Gemini to generate this episode description, and ChatGPT to generate the cover art!
Featured public domain music: Alpha Hydrae, Won't see it comin'.

Friday Mar 21, 2025
IHC Talk: Soft Tissue with Dr. David Papke
Friday Mar 21, 2025
Friday Mar 21, 2025
The Chromogen Siblings are back to talk about soft tissue sarcoma diagnosis and classification. Drs. Mike Arnold (@MArnold_PedPath), Andrew Bellizzi (@IHC_guy), and Sanam Loghavi (@sanamloghavi) speak with Dr. David Papke of Harvard University. Hear about his work and thoughts on identifying new diagnostic entities in soft tissue pathology. We also hear his remembrance of the late Dr. Christopher Fletcher and the influence Dr. Fletcher had on his career and the field of soft tissue pathology.
Featured public domain music: Alpha Hydrae, Won't see it comin'.

Friday Feb 21, 2025
PathPod Listens to the Pediatric and Developmental Pathology Podcast
Friday Feb 21, 2025
Friday Feb 21, 2025
In this episode, Dr. Margaret Collins of Cincinnati Children's Hospital speaks hosts Dr. Jason Wang and Dr. Michael Arnold (@MArnold_PedPath) about the Pediatric and Developmental Pathology Podcast. Hear about the journal Pediatric and Developmental Pathology, and what makes it unique. We also listen back to the first episode of the Pediatric and Developmental Pathology Podcast, featuring a conversation about the article co-authored by Dr. Collins, Eosinophilic Gastrointestinal Disorders: A New Path.
Featured public domain music: Main Stem by US Army Blues

Friday Jan 17, 2025
PathPod Looks Back at Episode 1 of the Diversify in Path Podcast
Friday Jan 17, 2025
Friday Jan 17, 2025
In this episode, Dr. Michael Williams (@bluehatcomics85) and Dr. Nicole Jackson (@NicoleJacksonMD) talk with hosts Dr. Michael Arnold (@MArnold_PedPath) and Dr. Sara Jiang (@Sara_Jiang) about how the Diversify In Path podcast got started, why the podcast is important and how the series remains as relevant as ever! We also listen back to Diversify In Path Season 1 Episode 1.
Featured public domain music: Main Stem by US Army Blues

Friday Dec 20, 2024
Beyond the Scope: Cytopathology with Dr. Ritu Nayar
Friday Dec 20, 2024
Friday Dec 20, 2024
In this segment, Beyond the Scope, we speak to pathologists about their pursuits and interests in and outside of pathology.
Links to papers referenced in the episode:
- Nayar, R. Cervical cancer prevention in the United States—where we've been and where we're going: The American Cancer Society Primary HPV Screening Initiative. Cancer Cytopathology https://doi.org/10.1002/cncy.22733
- Implementation in action: Collaborating on the transition to primary HPV screening for cervical cancer in the United States - PubMed (nih.gov).
CA Cancer J Clin . 2023 Sep-Oct;73(5):458-460. doi: 10.3322/caac.21786. Epub 2023 Jun 22.
- The time has come to implement primary human papillomavirus screening for cervical cancer in the United States - Franco - 2023 - Cancer - Wiley Online Library.
- Nayar, R. Precision Prevention: The 2019 ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors. J. Mol. Pathol. 2021, 2, 274-280. https://doi.org/10.3390/jmp2030023

Friday Nov 15, 2024
Around The Scope: Pediatric Pathology Fellowship
Friday Nov 15, 2024
Friday Nov 15, 2024
In this series, PathPod gathers pathologists Around The Scope to discuss their work in depth. In this episode, Dr. Vidyadhari Karne, a pathology resident at the University of Southern California, speaks with recent pediatric pathology fellows Dr. Lauren Kroll-Wheeler of Seattle Children's Hospital and Dr. Catherine Gestrich of Children's Hospital of Pittsburgh. What is different about fellowship compared with residency? What is it like to transition to practice as an attending?
Featured public domain music: Main Stem by US Army Blues

Thursday Nov 17, 2022
Around The Scope: Pathology in a Post-Roe World
Thursday Nov 17, 2022
Thursday Nov 17, 2022
In this series, PathPod gathers pathologists Around The Scope to discuss their work in depth. In this episode, we hear from the authors of a Letter to the Editor: Pathology and Abortion Rights Advocacy: Considerations in a Post-Roe World, published in the American Journal of Clinical Pathology (@ajcpjournal). Dr. Mike Arnold (@MArnold_PedPath) speaks with authors Dr. Jeremy Jacobs (@jwjacobs12), Dr. Nicole Jackson (@NicoleJacksonMD), Dr. Anne Mills (@AnneMillsMD), Dr. Elisheva Shanes (@ElishevaShanes), and Dr. Garrett Booth (@DrGSBooth1) about how the end of Roe v. Wade has impacted patient care pathologists provide, from perinatal pathology, cancer diagnosis and treatment, transfusion medicine, to forensic and autopsy pathology.
Featured public domain music: Main Stem by US Army Blues